BackgroundStructured, systematic methods to formulate consensus recommendations, such as the Delphi process or nominal group technique, among others, provide the opportunity to harness the knowledge of experts to support clinical decision making in areas of uncertainty. They are widely used in biomedical research, in particular where disease characteristics or resource limitations mean that high-quality evidence generation is difficult. However, poor reporting of methods used to reach a consensus – for example, not clearly explaining the definition of consensus, or not stating (...) how consensus group panellists were selected – can potentially undermine confidence in this type of research and hinder reproducibility. Our objective is therefore to systematically develop a reporting guideline to help the biomedical research and clinical practice community describe the methods or techniques used to reach consensus in a complete, transparent, and consistent manner.MethodsThe ACCORD project will take place in five stages and follow the EQUATOR Network guidance for the development of reporting guidelines. In Stage 1, a multidisciplinary Steering Committee has been established to lead and coordinate the guideline development process. In Stage 2, a systematic literature review will identify evidence on the quality of the reporting of consensus methodology, to obtain potential items for a reporting checklist. In Stage 3, Delphi methodology will be used to reach consensus regarding the checklist items, first among the Steering Committee, and then among a broader Delphi panel comprising participants with a range of expertise, including patient representatives. In Stage 4, the reporting guideline will be finalised in a consensus meeting, along with the production of an Explanation and Elaboration document. In Stage 5, we plan to publish the reporting guideline and E&E document in open-access journals, supported by presentations at appropriate events. Dissemination of the reporting guideline, including a website linked to social media channels, is crucial for the document to be implemented in practice.DiscussionThe ACCORD reporting guideline will provide a set of minimum items that should be reported about methods used to achieve consensus, including approaches ranging from simple unstructured opinion gatherings to highly structured processes. (shrink)

With this important volume, Karen Houle and Jim Vernon have done a masterful job at assembling a collection of essays on a topic which, until recently, has gone undeservedly neglected in contemporary scholarship—the relationship between German Idealist, G. W. F. Hegel, and twentieth Century French philosopher, Gilles Deleuze. The relationship between these two thinkers has been neglected in favor of Deleuze’s relationship to other historical figures , and Hegel’s relationship to other contemporary figures . In this context, the present volume (...) not only impressively represents some of the best scholarship on the relationship between German Idealism and contemporary French philosophy, but also has now come to form a substantial portion of research on the topic of the relationship between Hegel and Deleuze, in particular. A notable exception to this neglect is the recent book by Henry Somers-Hall, Hegel, Deleuze, and the Critique of Representati .. (shrink)

Comparative study of Hinduism and Sikhism.

Resumen El artículo busca presentar los fundamentos de una teoría de la desigualdad en Husserl a partir de una ampliación del concepto, proveniente de la ética husserliana, de destino. En las dos primeras secciones, presento las principales conclusiones de la ética de Husserl, incluyendo lo que hasta ahora la literatura ha entendido como el concepto de destino (que caracterizo como «destino natural»). Posteriormente, basándome en textos póstumos de Husserl, sugiero la necesidad de ampliar el ámbito del destino a su dimensión (...) social (lo que he denominado «destino social»), lo que hará posible apreciar que la desigualdad es un problema central para las preocupaciones prácticas de Husserl. Finalizo mostrando un sentido en que el destino social tiene cierta preeminencia sobre el destino natural. (shrink)

This article offers a state of the art of research on Husserl's political philosophy. I begin my work outlining historical and systematical reasons about why this area is not only underdeveloped but also that its discoveries are not systematized. Then, I indicate that there have been two major tendencies on how to understand Husserlian political philosophy, on the one hand, as an ontology of the political world and, on the other, as a branch of social ethics. I detail the main (...) contributions that have been offered in both tendencies and I argue why only the second of them can be considered in a strict sense the political philosophy of Husserl. (shrink)

Using a fictional but representative general practice consultation, involving the diagnosis of irritable bowel syndrome in a patient who is anxious for some relief from the discomfort his condition entails, this paper argues that when both a drug fails to out-perform placebo and the condition in question is a functional illness with no demonstrable underlying pathology, then the action of the drug is not only no better than placebo, and it is also no different from it either. The paper also (...) argues that, in the circumstances of the consultation described, it is striking that current governance deems it ethical for a practitioner to prescribe either a drug or a placebo, both of which appear to rely for their effectiveness on a measure of concealment on the part of the doctor, yet deems it unethical for a practitioner openly to prescribe a harmless and enjoyable substance which is likely to be no less effective than either drug or placebo and is also likely to be better-tolerated and cheaper than the drug. (shrink)

While seeking novel food sources to feed the increasing population of the globe, several alternatives have been discussed, including algae, fungi or in vitro meat. The increasingly propagated usage of farmed insects for human nutrition raises issues regarding food safety, consumer information and animal protection. In line with law, insects like any other animals must not be reared or manipulated in a way that inflicts unnecessary pain, distress or harm on them. Currently, there is a great need for research in (...) the area of insect welfare, especially regarding species-specific needs, health, farming systems and humane methods of killing. Recent results from neurophysiological, neuroanatomical and behavioral sciences prompt caution when denying consciousness and therefore the likelihood of presence of pain and suffering or something closely related to it to insects. From an animal protection point of view, these issues should be satisfyingly solved before propagating and establishing intensive husbandry systems for insects as a new type of mini-livestock factory farming. (shrink)

Bernhard and Young (Journal of Academic Ethics, 7, 175-191, 2009) allege that a myth of confidentiality plagues research in North America because of the absence of statute-based legal protections and the requirements of some REBs to limit confidentiality to the extent permitted by law. In this commentary we describe statute-based protections for research confidentiality available in the United States, clarify the legal situation regarding research confidentiality in Canada, and explain that REBs that require confidentiality to be limited by law are (...) imposing a doctrine that is not required by the TCPS and may violate researchers’ academic freedom. The paper laments how excessive REB risk aversion and inaction by the granting agency Presidents has created a situation where some REBs are encouraging researchers to download research risks to research participants and forcing researchers to choose between exposing themselves to the prospect of going to jail to protect confidentiality, watering down their research objectives, or conducting vanilla research rather than engaging in controversial and/or sensitive areas of study. The paper urges the granting agency Presidents to seek legislative change to protect research participants who provide information that could cause them harm if their identity were to be revealed. (shrink)

Reproduction and immunity are energy intensive, intimately linked processes in most organisms. In women, pregnancy is associated with widespread immunological adaptations that alter immunity to many diseases, whereas, immune dysfunction has emerged as a major cause for infertility in both men and women. Deciphering the molecular bases of this dynamic association is inherently challenging in mammals. This relationship has been traditionally studied in fast‐living, invertebrate species, often in the context of resource allocation between life history traits. More recently, these studies (...) have advanced our understanding of the mechanistic underpinnings of the immunity‐fertility dialogue. Here, we review the molecular connections between reproduction and immunity from the perspective of human pregnancy to mechanistic discoveries in laboratory organisms. We focus particularly on recent invertebrate studies identifying conserved signaling pathways and transcription factors that regulate resource allocation and shape the balance between reproductive status and immune health. (shrink)

The goal of this paper is to show how culture – shared norms and values – is challenged and used to facilitate cooperative behavior within the context of farmer field schools (FFS) in central Luzon, Philippines. The success of the FFS is primarily associated with cultural norms that encourage experiential and collective learning and eventually lead to the adoption of integrated pest management (IPM) methods among the farmers. The study was conducted in central Luzon, the rice granary region of the (...) Philippines, from 1992 to 1995 and again in 1999. Both qualitative and quantitative research methods were employed. Results indicate that a keen understanding of Filipino culture and values is essential if FFS is to be successful and if farmers are to successfully learn and practice IPM. (shrink)

The purpose of this study is to train an artificial neural network model for predicting student failure in the academic leveling course of the Escuela Politécnica Nacional of Ecuador, based on academic and socioeconomic information. For this, 1308 higher education students participated, 69.0% of whom failed the academic leveling course; besides, 93.7% of the students self-identified as mestizo, 83.9% came from the province of Pichincha, and 92.4% belonged to general population. As a first approximation, a neural network model was trained (...) with twelve variables containing students’ academic and socioeconomic information. Then, a dimensionality reduction process was performed from which a new neural network was modeled. This dimension reduced model was trained with the variables application score, vulnerability index, regime, gender, and population segment, which were the five variables that explained more than 80% of the first model. The classification accuracy of the dimension reduced model was 0.745, while precision and recall were 0.883 and 0.778, respectively. The area under ROC curve was 0.791. This model could be used as a guide to lead intervention policies so that the failure rate in the academic leveling course would decrease. (shrink)

Conflict is inevitable within congregations and can contribute to their growth or decline, depending on how the leadership in a congregation handles a conflict. The Dutch Reformed Church in Africa, Orange Free State (DRCA OFS) has, for over a decade, experienced growing internal conflicts within its leadership in the various structures of the church. Some of these conflicts have culminated in physical violence and litigations. This article aims to analyse the emerging conflict situations within the leadership in the various structures (...) of the DRCA OFS. The leading research question is: What are the dynamics of conflict situations of the leadership in the various structures of the DRCA OFS? (shrink)

1. (no separate title) -- 2. Khristii︠a︡nska antropologii︠a︡. Filosofii︠a︡ na morala i khristiia︡nskata etika.

Wheeler–deWitt equation as well as some relevant current research (Chiou’s timeless path integral approach for relativistic quantum mechanics; Palmer’s view of a fundamental level of physical reality based on an Invariant Set Postulate; Girelli’s, Liberati’s and Sindoni’s toy model of a non-dynamical timeless space as fundamental background of physical events) suggest that at a fundamental level the background space of physics is timeless, that the duration of physical events has not a primary existence. By taking into consideration the two fundamental (...) theories of time represented by the Jacobi-Barbour-Bertotti theory and by Rovelli’s approach, here it is shown that the view of time as emergent quantity measuring the numerical order of material changes (which can above all be derived from some significant current research, such as Elze’s approach of time, Caticha’s approach of entropic time and Prati’s model of physical clock time) introduces a suggestive unifying re-reading. (shrink)

A level of adequacy of a given model with physical world represents an important element of physics. In an “ideal” model each element in the model would correspond exactly to one element in the physical world. In such a model each element would have a direct epistemological correlation with exactly one element of the physical world. Such a model would become a perfect picture of the physical world. The possibility of misinterpretation, in a sense that one searches for physical existence (...) of purely theoretically predicted elements of the model, would be excluded. In order to develop such a model we apply bijective function of set theory. Bijective function applied on time research shows model of space–time has no direct epistemological correlation in physical reality. Time is duration of changes which run in space. Duration does not run in time, duration is time. (shrink)

Research confidentiality in Britain is under attack. Indeed, in some quarters the ‘Law of the Land’ doctrine that absolutely subjugates research ethics to law is already a fait accompli. To illustrate the academic freedom issues at stake, the article discusses: the Cambridge Psychology Research Ethics Committee’s ban of interview questions about a research participant’s involvement in criminal acts; the awarding of damages against Exeter University when it reneged on its agreement to uphold a doctoral student’s guarantee of ‘absolute confidentiality’ in (...) his research on assisted suicide; and the controversy around the UK government’s attempt to obtain confidential records from the Belfast Project − an oral history of paramilitaries involved in the Troubles in Northern Ireland. The article urges British researchers to practice – or, at least, defend the academic freedom of their colleagues to practice – the ‘ethics-first’ doctrine of strict confidentiality that several North American disciplinary associations encourage. (shrink)

Although in the US there have been dozens of subpoenas seeking information gathered by academic researchers under a pledge of confidentiality, few cases have garnered as much attention as the two sets of subpoenas issued to Boston College seeking interviews conducted with IRA operatives who participated in The Belfast Project, an oral history of The Troubles in Northern Ireland. For the researchers and participants, confidentiality was understood to be unlimited, while Boston College has asserted that it pledged confidentiality only “to (...) the extent American law allows.” This a priori limitation to confidentiality is invoked by many researchers and universities in the United States, Canada and Great Britain, but there has been little discussion of what the phrase means and what ethical obligations accompany it. An examination of the researchers’ and Boston College’s behaviour in relation to the subpoenas provides the basis for that discussion. We conclude that Boston College has provided an example that will be cited for years to come of how not to protect research participants to the extent American law allows. (shrink)

In “Advisory Opinion on Confidentiality, Its Limits and Duties to Others” the Canadian Interagency Advisory Panel on Research Ethics (PRE) articulates a rationale for a priori limitations to research confidentiality, based largely on putative legal duties to violate confidentiality in certain circumstances. We argue that PRE promotes a “Law of the Land” doctrine of research ethics that is but one approach to resolving potential conflicts between law and research ethics. PRE emphasises risks that have never materialized, and ignores jurisprudence on (...) challenges to research confidentiality. When we examine what the courts have actually done with research-based claims of privilege, we find they clearly recognize and affirm researchers’ ethical obligations to maintain strict confidentiality and protect research participants. Ironically, the one exception – where the court ordered that information be disclosed – occurred precisely because the researchers had limited confidentiality. The passive approach PRE espouses leaves vital questions about what protecting confidentiality to the “full extent possible in law” means, and leaves the impression that academics should accept whatever limitations the courts may impose without participating in the courtroom dialogue determining where those limits are drawn. In contrast, we believe confidentiality is so important to the protection of research participants and the integrity of the research enterprise that it is worth fighting for. The “ethics-first” doctrine of “strict confidentiality” we describe adheres to the social sciences’ and humanities’ longstanding commitment to research confidentiality and duty to the research participant. (shrink)

Rice crop diversity hasdecreased dramatically in the recent past.Understanding the causes that underlie theevident genetic erosion is critical for thefood security of subsistence rice farmers andbiodiversity. Our study shows that farmers inthe northeastern Philippines had a markedreduction in rice diversity from 1996 to 1998.The ultimate causes were a drought resultingfrom the El Niño phenomenon in 1997 andflooding due to two successive typhoons in1998. The proximate causes, however, includedlocal water control factors, limitations in thehousehold and village-level seedinfrastructure, farm location in relation (...) tothe goods and services necessary to obtainseeds, policies and programs of the Departmentof Agriculture, and the characteristics of therice varieties themselves. The implications ofour study are that genetic erosion is notalways the result of purposeful acts by farmersnor is it necessarily gradual. Improvingon-farm seed technology will stabilize the seedproduction, distribution, and use system andthereby enhance household food security.Ultimately, rice diversity will be improvedonly if diversity is a safe and viable optionfor farmers. Therefore, public policy thatsupports farmers who maintain a diverse set ofcultivars is critical for any on-farmconservation strategy. (shrink)

People may exhibit two kinds of modifications when demonstrating action for others: modifications to facilitate bottom‐up, or sensory‐based processing; and modifications to facilitate top‐down, or knowledge‐based processing. The current study examined actors' production of such modifications in action demonstrations for audiences that differed in their capacity for intentional reasoning. Actors' demonstrations of complex actions for a non‐anthropomorphic computer system and for people (adult and toddler) were compared. Evidence was found for greater highlighting of top‐down modifications in the demonstrations for the (...) human audiences versus the computer audience. Conversely, participants highlighted simple perceptual modifications for the computer audience, producing more punctuated and wider ranging motions. This study suggests that people consider differences in their audiences when demonstrating action. (shrink)

Pali Buddhist Texts-explained to the Beginner. Rune. E. A. Johansson. Scandinavian Institute of Asian Studies Monograph Series No. 14 Curzon Press, London, Second edition, revised and enlarged, 1977 160 pp. £4.00.

In this paper, I provide a philosophical analysis of Pāli texts that treat of a special kind of mental event called bhavaṅga citta. This mental event is a primal sentient consciousness, a passive form of basal awareness that individuates sentient beings as the type of being that they are. My aims with this analysis are twofold, one genealogical and reconstructive, the other systematic. On the genealogical and reconstructive side, I argue for a distinction between two kinds of continuity that are (...) at work in explaining the temporal structure of experience in Pāli Buddhist philosophy. Call these two forms of continuity ‘diachronic’ and ‘affective-motivational’ continuity, respectively. In my analysis of these two forms of continuity, I will focus on the coherence of bhavaṅga citta in its Abhidhammic context. My contention is that the commentarial account of bhavaṅga citta has the resources to explain diachronic continuity but struggles to give a fully workable account of affective-motivational continuity. I argue that the novel view of mental continuity offered by the early twentieth century Burmese monastic exegete Ledi Sayadaw offers another intriguing account of mental continuity, one that can help to explain affective-motivational continuity. Systematically speaking, in spelling out the dynamics of this distinction between types of mental continuity in connection with bhavaṅga, I offer a cross-cultural philosophical analysis of the deep structure of the mind and how affective processes below the threshold of ordinary habits of attention have a profound conditioning effect on our conscious relationship with the world. (shrink)

Wörterbuch Pali-Deutsch. Mit Sanskrit-Index. Klaus Mylius. Institut für Indologie, Wichtrach 1997. 438 pp. SFr.180. ISBN 3-7187-0019-0.

And the Bactrian King, a possible convert to Buddhism, responds at this point, " Well said, Nagasena! So it is, and as such I accept it." Conclusion Between the times of these two apparently contradictory texts about nirvana, the Mahavagga and ...

Pali Buddhist Texts explained to the beginner. Rune E. A. Johansson. Scandinavian Institute of Aisan Studies Monograph Series No. 14, Copenhagen. 152 pp. £3.30.

Deutsch-Pali Wörterbuch. Helmut Klar. Octopus Verlag, Vienna 1982. 364pp.

Pali Buddhism. Edited by Frank J. Hoffman and Deegalle Mahinda. Curzon Press, Richmond 1996. 233 pp. £40. ISBN 0-7007-0359-4.

Pali Literature, including the Canonical Literature in Prakrit and Sanskrit of all the Hinayana Schools. K. R. Norman. Vol.VII, fasc.2, of A History of Indian Literature ed. Jan Gonda. Otto Harrassowitz, Wiesbaden 1983. X + 210pp. DM 98.

In this paper, I provide a philosophical analysis of Pāli texts that treat of a special kind of mental event called bhavaṅga citta. This mental event is a primal sentient consciousness, a passive form of basal awareness that individuates sentient beings as the type of being that they are. My aims with this analysis are twofold, one genealogical and reconstructive, the other systematic. On the genealogical and reconstructive side, I argue for a distinction between two kinds of continuity that are (...) at work in explaining the temporal structure of experience in Pāli Buddhist philosophy. Call these two forms of continuity ‘diachronic’ and ‘affective-motivational’ continuity, respectively. In my analysis of these two forms of continuity, I will focus on the coherence of bhavaṅga citta in its Abhidhammic context. My contention is that the commentarial account of bhavaṅga citta has the resources to explain diachronic continuity but struggles to give a fully workable account of affective-motivational continuity. I argue that the novel view of mental continuity offered by the early twentieth century Burmese monastic exegete Ledi Sayadaw (1846–1923) offers another intriguing account of mental continuity, one that can help to explain affective-motivational continuity. Systematically speaking, in spelling out the dynamics of this distinction between types of mental continuity in connection with bhavaṅga, I offer a cross-cultural philosophical analysis of the deep structure of the mind and how affective processes below the threshold of ordinary habits of attention have a profound conditioning effect on our conscious relationship with the world. (shrink)